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Target
Interleukin-17F
Ligand
BDBM261505
Substrate
n/a
Meas. Tech.
TH17 Cytokine Inhibition ELISA
IC50
>10000±n/a nM
Citation
 Gaweco, A; Tilley, JW; Walker, J; Palmer, S; Blinn, J ROR modulators and their uses US Patent  US9708268 Publication Date 7/18/2017
Target
Name:
Interleukin-17F
Synonyms:
Cytokine ML-1 | IL17F | IL17F_HUMAN | il-17f
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18053.35
Organism:
Homo sapiens (Human)
Description:
Q96PD4
Residue:
163
Sequence:
MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
  
Inhibitor
Name:
BDBM261505
Synonyms:
1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl)-2-oxo-1,2-dihydroquinoline-6-carboxamide | US9708268, 8
Type:
Small organic molecule
Emp. Form.:
C15H12BrNO
Mol. Mass.:
302.166
SMILES:
Brc1ccc(NC(=O)\C=C\c2ccccc2)cc1
Structure:
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