Target
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2)
Ligand
BDBM39048
Substrate
n/a
Meas. Tech.
Dose-response cell-based assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)
IC50
3974±n/a nM
Citation
 PubChem, PC Dose-response cell-based assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA) PubChem Bioassay (2007)[AID]
Target
Name:
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2)
Synonyms:
NR1F1 | Nuclear receptor ROR-alpha | Nuclear receptor ROR-alpha (Alpha-2) | Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). | RORA | RORA_HUMAN | RZRA
Type:
PROTEIN
Mol. Mass.:
63033.59
Organism:
Homo sapiens (Human)
Description:
EBI_101591
Residue:
556
Sequence:
MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCILSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
  
Inhibitor
Name:
BDBM39048
Synonyms:
5-(2-chloranyl-4-methyl-phenyl)-3-phenyl-1,2,4-oxadiazole | 5-(2-chloro-4-methyl-phenyl)-3-phenyl-1,2,4-oxadiazole | 5-(2-chloro-4-methylphenyl)-3-phenyl-1,2,4-oxadiazole | MLS000115426 | SMR000092530 | cid_2056784
Type:
Small organic molecule
Emp. Form.:
C15H11ClN2O
Mol. Mass.:
270.714
SMILES:
Cc1ccc(-c2nc(no2)-c2ccccc2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: