Reaction Details  Report a problem with these data
Target
Dual specificity protein phosphatase 6
Ligand
BDBM38837
Substrate
n/a
Meas. Tech.
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-3 Dose Response Selectivity comparison.
IC50
19763±n/a nM
Citation
 PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-3 Dose Response Selectivity comparison. PubChem Bioassay (2007)[AID]
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rat
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM38837
Synonyms:
2-(2-phenylethyl)-4H-isoquinoline-1,3-dione | 2-phenethyl-4H-isoquinoline-1,3-quinone | MLS000119149 | SMR000096084 | cid_713096
Type:
Small organic molecule
Emp. Form.:
C17H15NO2
Mol. Mass.:
265.3065
SMILES:
O=C1Cc2ccccc2C(=O)N1CCc1ccccc1
Structure:
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