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Target
Beta-lactamase
Ligand
BDBM50202233
Substrate
n/a
Meas. Tech.
Enzyme Inhibition Assay
pH
7±0
Ki
1.62e+5±n/a nM
Citation
 Caselli, E; Powers, RA; Blasczcak, LC; Wu, CY; Prati, F; Shoichet, BK Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases. Chem Biol 8:17-31 (2001) [PubMed]  Article
Target
Name:
Beta-lactamase
Synonyms:
BLAC_STAAU | Beta-lactamase TEM | Penicillinase | blaZ
Type:
PROTEIN
Mol. Mass.:
31367.53
Organism:
Staphylococcus aureus
Description:
ChEMBL_41052
Residue:
281
Sequence:
MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALDTKSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKKFLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
  
Inhibitor
Name:
BDBM50202233
Synonyms:
Acylglycineboronic acid, 5 | CHEMBL227673 | acetamidomethylboronic acid
Type:
Small organic molecule
Emp. Form.:
C3H8BNO3
Mol. Mass.:
116.912
SMILES:
CC(=O)NCB(O)O
Structure:
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