Reaction Details  Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM39557
Substrate
n/a
Meas. Tech.
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
EC50
4381±n/a nM
Citation
 PubChem, PC Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID]
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM39557
Synonyms:
5-amino-1-(4-bromo-2-fluoro-benzyl)-N-(3-methoxyphenyl)triazole-4-carboxamide | 5-amino-1-[(4-bromo-2-fluorophenyl)methyl]-N-(3-methoxyphenyl)-4-triazolecarboxamide | 5-amino-1-[(4-bromo-2-fluorophenyl)methyl]-N-(3-methoxyphenyl)triazole-4-carboxamide | 5-azanyl-1-[(4-bromanyl-2-fluoranyl-phenyl)methyl]-N-(3-methoxyphenyl)-1,2,3-triazole-4-carboxamide | MLS000117971 | SMR000094919 | cid_5307774
Type:
Small organic molecule
Emp. Form.:
C17H15BrFN5O2
Mol. Mass.:
420.236
SMILES:
COc1cccc(NC(=O)c2nnn(Cc3ccc(Br)cc3F)c2N)c1
Structure:
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