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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42219
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID]
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42219
Synonyms:
2-(4-methylanilino)-3-(4-morpholinyl)naphthalene-1,4-dione | 2-(4-methylanilino)-3-morpholin-4-ylnaphthalene-1,4-dione | 2-Morpholin-4-yl-3-p-tolylamino-[1,4]naphthoquinone | 2-[(4-methylphenyl)amino]-3-morpholin-4-yl-naphthalene-1,4-dione | 2-morpholino-3-(p-toluidino)-1,4-naphthoquinone | MLS000557780 | SMR000178047 | cid_2893413
Type:
Small organic molecule
Emp. Form.:
C21H20N2O3
Mol. Mass.:
348.3951
SMILES:
Cc1ccc(NC2=C(N3CCOCC3)C(=O)c3ccccc3C2=O)cc1 |c:6|
Structure:
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