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Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM46038
Substrate
n/a
Meas. Tech.
SAR analysis of an In Vitro TNAP Dose Response Luminescent Assay
IC50
>100000±n/a nM
Citation
 PubChem, PC SAR analysis of an In Vitro TNAP Dose Response Luminescent Assay PubChem Bioassay (2010)[AID]
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM46038
Synonyms:
4-(3-keto-1,2-benzothiazol-2-yl)benzoic acid ethyl ester | 4-(3-oxo-1,2-benzothiazol-2-yl)benzoic acid ethyl ester | MLS-0315808.0001 | cid_2467794 | ethyl 4-(3-oxidanylidene-1,2-benzothiazol-2-yl)benzoate | ethyl 4-(3-oxo-1,2-benzothiazol-2-yl)benzoate
Type:
Small organic molecule
Emp. Form.:
C16H13NO3S
Mol. Mass.:
299.344
SMILES:
CCOC(=O)c1ccc(cc1)-n1sc2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: