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Target
Alkaline phosphatase, germ cell type
Ligand
BDBM46048
Substrate
n/a
Meas. Tech.
Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase confirmation
IC50
15800±n/a nM
Citation
 PubChem, PC Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase confirmation PubChem Bioassay (2009)[AID]
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM46048
Synonyms:
1-[3,4-bis(oxidanyl)phenyl]-2-(4-bromanylimidazol-1-yl)ethanone;hydrochloride | 2-(4-bromo-1-imidazolyl)-1-(3,4-dihydroxyphenyl)ethanone;hydrochloride | 2-(4-bromoimidazol-1-yl)-1-(3,4-dihydroxyphenyl)ethanone;hydrochloride | CHEMBL597028 | MLS-0315846.0001 | cid_25067479
Type:
Small organic molecule
Emp. Form.:
C11H9BrN2O3
Mol. Mass.:
297.105
SMILES:
Oc1ccc(cc1O)C(=O)Cn1cnc(Br)c1
Structure:
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