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Target
Procathepsin L
Ligand
BDBM32756
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response testing in the presence of cysteine
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin L dose-response testing in the presence of cysteine PubChem Bioassay (2009)[AID]
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM32756
Synonyms:
2-furancarboxylic acid [5-amino-1-(4-fluorophenyl)sulfonyl-3-pyrazolyl] ester | CHEMBL245265 | Furan-2-carboxylic acid 5-amino-1-(4-fluoro-benzenesulfonyl)-1H-pyrazol-3-yl ester | MLS000033900 | SMR000014918 | US11584714, Compound 44# | [5-amino-1-(4-fluorophenyl)sulfonylpyrazol-3-yl] furan-2-carboxylate | [5-azanyl-1-(4-fluorophenyl)sulfonyl-pyrazol-3-yl] furan-2-carboxylate | cid_647599 | furan-2-carboxylic acid [5-amino-1-(4-fluorophenyl)sulfonyl-pyrazol-3-yl] ester
Type:
Small organic molecule
Emp. Form.:
C14H10FN3O5S
Mol. Mass.:
351.31
SMILES:
Nc1cc(OC(=O)c2ccco2)nn1S(=O)(=O)c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: