Reaction Details  Report a problem with these data
Target
Phosphoethanolamine/phosphocholine phosphatase
Ligand
BDBM34791
Substrate
n/a
Meas. Tech.
SAR assay for compounds that inhibit PHOSPHO1
IC50
4470±n/a nM
Citation
 PubChem, PC SAR assay for compounds that inhibit PHOSPHO1 PubChem Bioassay (2010)[AID]
Target
Name:
Phosphoethanolamine/phosphocholine phosphatase
Synonyms:
PHOP1_HUMAN | PHOSPHO1 | phosphatase, orphan 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29718.09
Organism:
Homo sapiens (Human)
Description:
Q8TCT1
Residue:
267
Sequence:
MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVILISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKSC
  
Inhibitor
Name:
BDBM34791
Synonyms:
MLS000392355 | N-methyl-2-(4-methylphenyl)-3-phenyl-1,2,4-thiadiazol-2-ium-5-amine;bromide | SMR000261243 | cid_12006282 | methyl-[3-phenyl-2-(p-tolyl)-1,2,4-thiadiazol-2-ium-5-yl]amine;bromide
Type:
Small organic molecule
Emp. Form.:
C16H16N3S
Mol. Mass.:
282.383
SMILES:
CNc1nc(-c2ccccc2)[n+](s1)-c1ccc(C)cc1
Structure:
Search PDB for entries with ligand similarity: