Reaction Details  Report a problem with these data
Target
Regulator of G-protein signaling 8
Ligand
BDBM47710
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID]
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47710
Synonyms:
(5-methyl-1,2-oxazol-3-yl)-[4-(2-phenylethyl)piperazin-1-yl]methanone | (5-methyl-3-isoxazolyl)-[4-(2-phenylethyl)-1-piperazinyl]methanone | (5-methylisoxazol-3-yl)-(4-phenethylpiperazino)methanone | 1-[(5-methyl-3-isoxazolyl)carbonyl]-4-(2-phenylethyl)piperazine | MLS000099809 | SMR000080791 | cid_1247515
Type:
Small organic molecule
Emp. Form.:
C17H21N3O2
Mol. Mass.:
299.3675
SMILES:
Cc1cc(no1)C(=O)N1CCN(CCc2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: