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Target
Regulator of G-protein signaling 16
Ligand
BDBM47726
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID]
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47726
Synonyms:
3-[(5-methyl-2-pyridyl)carbamoyl]-5-nitro-benzoic acid methyl ester | 3-[[(5-methyl-2-pyridinyl)amino]-oxomethyl]-5-nitrobenzoic acid methyl ester | MLS000561314 | N-(5-Methyl-pyridin-2-yl)-5-nitro-isophthalamic acid methyl ester | SMR000177252 | cid_798633 | methyl 3-[(5-methylpyridin-2-yl)carbamoyl]-5-nitro-benzoate | methyl 3-[(5-methylpyridin-2-yl)carbamoyl]-5-nitrobenzoate
Type:
Small organic molecule
Emp. Form.:
C15H13N3O5
Mol. Mass.:
315.2808
SMILES:
COC(=O)c1cc(cc(c1)[N+]([O-])=O)C(=O)Nc1ccc(C)cn1
Structure:
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