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Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM43863
Substrate
n/a
Meas. Tech.
Homologous recombination_Rad 51_dose response_2
IC50
53000±n/a nM
Citation
 PubChem, PC Homologous recombination_Rad 51_dose response_2 PubChem Bioassay (2008)[AID]
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM43863
Synonyms:
3-[[4-amino-6-(2,5-dimethoxyanilino)-5-nitro-pyrimidin-2-yl]amino]propyl-dimethyl-amine | 4-N-(2,5-dimethoxyphenyl)-2-N-[3-(dimethylamino)propyl]-5-nitropyrimidine-2,4,6-triamine | Glycopeptide, 3a | MLS000333423 | N'-(2,5-Dimethoxy-phenyl)-N-(3-dimethylamino-propyl)-5-nitro-pyrimidine-2,4,6-triamine | N4-(2,5-dimethoxyphenyl)-N2-[3-(dimethylamino)propyl]-5-nitro-pyrimidine-2,4,6-triamine | N4-(2,5-dimethoxyphenyl)-N2-[3-(dimethylamino)propyl]-5-nitropyrimidine-2,4,6-triamine | SMR000436735 | cid_3642542
Type:
Peptide
Emp. Form.:
C17H25N7O4
Mol. Mass.:
391.4249
SMILES:
COc1ccc(OC)c(Nc2nc(NCCCN(C)C)nc(N)c2[N+]([O-])=O)c1
Structure:
Search PDB for entries with ligand similarity: