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Target
Zinc finger protein mex-5
Ligand
BDBM4810
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID]
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM4810
Synonyms:
(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one | 3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-indolin-2-one | CHEMBL276711 | SU5146 | SU5416 | Semaxanib | US10189853, semaxanib | US11111252, Compound SU5416 | US9422297, SU5416 | cid_5329098
Type:
Small organic molecule
Emp. Form.:
C15H14N2O
Mol. Mass.:
238.2845
SMILES:
Cc1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1
Structure:
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