Reaction Details  Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM18
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
13509±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID]
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM18
Synonyms:
(3-amino-5-methyl-6-phenyl-phenanthridin-5-ium-8-yl)amine;bromide | 3,8-diamino-5-methyl-6-phenylphenanthridin-5-ium bromide | 5-methyl-6-phenyl-phenanthridin-5-ium-3,8-diamine;bromide | 5-methyl-6-phenylphenanthridin-5-ium-3,8-diamine;bromide | Dimidium bromide | MLS001074889 | SMR000568409 | cid_68207 | ethidium bromide
Type:
Small organic molecule
Emp. Form.:
C20H18N3
Mol. Mass.:
300.3765
SMILES:
Cn1c(-c2ccccc2)c2cc(N)ccc2c2ccc(=[NH2+])cc12
Structure:
Search PDB for entries with ligand similarity: