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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM32098
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
1840±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID]
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Human
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM32098
Synonyms:
3-(2-methylanilino)-2H-isoquinolin-1-one | 3-(o-toluidino)isocarbostyril | 3-[(2-methylphenyl)amino]-2H-isoquinolin-1-one | 3-[(2-methylphenyl)amino]isoquinolin-1(2H)-one | MLS000043700 | SMR000020712 | cid_2142222
Type:
Small organic molecule
Emp. Form.:
C16H14N2O
Mol. Mass.:
250.2952
SMILES:
Cc1ccccc1Nc1cc2ccccc2c(=O)[nH]1
Structure:
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