Reaction Details  Report a problem with these data
Target
GTPase KRas [1-37]
Ligand
BDBM54699
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype PubChem Bioassay (2009)[AID]
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM54699
Synonyms:
4-(1-oxo-3-phenylprop-2-ynyl)benzonitrile | 4-(3-phenylprop-2-ynoyl)benzenecarbonitrile | 4-(3-phenylprop-2-ynoyl)benzonitrile | 4-(3-phenylpropioloyl)benzonitrile | UNM-0000306057 | cid_11708441
Type:
Small organic molecule
Emp. Form.:
C16H9NO
Mol. Mass.:
231.2488
SMILES:
O=C(C#Cc1ccccc1)c1ccc(cc1)C#N
Structure:
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