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Target
GTPase KRas [1-37]
Ligand
BDBM54696
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant
EC50
30000±n/a nM
Comments
Extracted from aid = 2043 and tid = 2
Citation
PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay (2009)[AID]
More Info.:
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE