Reaction Details  Report a problem with these data
Target
Eukaryotic translation initiation factor 4H
Ligand
BDBM61314
Substrate
n/a
Meas. Tech.
uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H)
IC50
100000±n/a nM
Citation
 PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay (2009)[AID]
Target
Name:
Eukaryotic translation initiation factor 4H
Synonyms:
EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27385.24
Organism:
Homo sapiens (Human)
Description:
Q15056
Residue:
248
Sequence:
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
  
Inhibitor
Name:
BDBM61314
Synonyms:
(1-methylpyridin-1-ium-2-yl)-(1-methyl-2-pyridylidene)amine;iodide | 1-Methyl-2-[1-methyl-1H-pyridin-(2E)-ylideneamino]-pyridinium | 1-methyl-N-(1-methyl-2-pyridin-1-iumyl)-2-pyridinimine;iodide | 1-methyl-N-(1-methylpyridin-1-ium-2-yl)pyridin-2-imine;iodide | MLS001030036 | SMR000427247 | cid_2848485
Type:
Small organic molecule
Emp. Form.:
C12H14N3
Mol. Mass.:
200.2591
SMILES:
Cn1ccccc1=Nc1cccc[n+]1C
Structure:
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