Reaction Details  Report a problem with these data
Target
Bcl-2-like protein 11
Ligand
BDBM43476
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis
EC50
7185±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay (2010)[AID]
Target
Name:
Bcl-2-like protein 11
Synonyms:
B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM
Type:
PROTEIN
Mol. Mass.:
22175.26
Organism:
Homo sapiens (Human)
Description:
EBI_101325
Residue:
198
Sequence:
MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
  
Inhibitor
Name:
BDBM43476
Synonyms:
1-methyl-4-[(2,3,4,5-tetrachloro-1-cyclopenta-2,4-dienylidene)methyl]benzene | 1-methyl-4-[(2,3,4,5-tetrachlorocyclopenta-2,4-dien-1-ylidene)methyl]benzene | 1-methyl-4-[[2,3,4,5-tetrakis(chloranyl)cyclopenta-2,4-dien-1-ylidene]methyl]benzene | MLS000738051 | SMR000393724 | cid_230812
Type:
Small organic molecule
Emp. Form.:
C13H8Cl4
Mol. Mass.:
306.015
SMILES:
[#6]-c1ccc(\[#6]=[#6]-2\[#6](Cl)=[#6](Cl)-[#6](Cl)=[#6]-2Cl)cc1 |c:12,t:8|
Structure:
Search PDB for entries with ligand similarity: