Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM76052
Substrate
n/a
Meas. Tech.
SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 4
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID]
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM76052
Synonyms:
MLS-0226851.0001 | N-[4-(diethylsulfamoyl)phenyl]-2-(2-thienyl)cinchoninamide | N-[4-(diethylsulfamoyl)phenyl]-2-thiophen-2-yl-4-quinolinecarboxamide | N-[4-(diethylsulfamoyl)phenyl]-2-thiophen-2-yl-quinoline-4-carboxamide | N-[4-(diethylsulfamoyl)phenyl]-2-thiophen-2-ylquinoline-4-carboxamide | cid_4803470
Type:
Small organic molecule
Emp. Form.:
C24H23N3O3S2
Mol. Mass.:
465.588
SMILES:
CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)-c2cccs2)cc1
Structure:
Search PDB for entries with ligand similarity: