Reaction Details  Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM39556
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
4590±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID]
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM39556
Synonyms:
5-[[3-(3,5-dimethyl-1-pyrazolyl)-6-methyl-2-quinoxalinyl]amino]-1,3-dihydrobenzimidazol-2-one | 5-[[3-(3,5-dimethylpyrazol-1-yl)-6-methyl-quinoxalin-2-yl]amino]-1,3-dihydrobenzimidazol-2-one | 5-[[3-(3,5-dimethylpyrazol-1-yl)-6-methylquinoxalin-2-yl]amino]-1,3-dihydrobenzimidazol-2-one | 5-{[3-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methyl-2-quinoxalinyl]amino}-1,3-dihydro-2H-benzimidazol-2-one | MLS000052231 | SMR000081644 | cid_1253520
Type:
Small organic molecule
Emp. Form.:
C21H19N7O
Mol. Mass.:
385.4219
SMILES:
Cc1cc(C)n(n1)-c1nc2cc(C)ccc2nc1Nc1ccc2[nH]c(=O)[nH]c2c1
Structure:
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