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Target
Beta-2 adrenergic receptor
Ligand
BDBM50001908
Substrate
n/a
Meas. Tech.
ChEBML_37833
IC50
56000±n/a nM
Citation
 Phillips, GB; Morgan, TK; Lumma, WC; Gomez, RP; Lind, JM; Lis, R; Argentieri, T; Sullivan, ME Synthesis, cardiac electrophysiology, and beta-blocking activity of novel arylpiperazines with potential as class II/III antiarrhythmic agents. J Med Chem 35:743-50 (1992) [PubMed]
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_CANLF
Type:
PROTEIN
Mol. Mass.:
46593.67
Organism:
Canis familiaris
Description:
ChEMBL_56504
Residue:
415
Sequence:
MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50001908
Synonyms:
1-(4-Nitro-phenyl)-piperazine | CHEMBL165012
Type:
Small organic molecule
Emp. Form.:
C10H13N3O2
Mol. Mass.:
207.2291
SMILES:
[O-][N+](=O)c1ccc(cc1)N1CCNCC1
Structure:
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