Reaction Details  Report a problem with these data
Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50013551
Substrate
n/a
Meas. Tech.
ChEBML_52211
Ki
40±n/a nM
Citation
 Huang, FC; Galemmo, RA; Johnson, WH; Poli, GB; Morrissette, MM; Mencel, JJ; Warus, JD; Campbell, HF; Nuss, GW; Carnathan, GW Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 2. Effects of an additional phenyl ring on receptor affinity. J Med Chem 33:1194-200 (1990) [PubMed]
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50013551
Synonyms:
3-[3-(Quinolin-2-ylmethoxy)-phenoxymethyl]-benzoic acid | CHEMBL18979
Type:
Small organic molecule
Emp. Form.:
C24H19NO4
Mol. Mass.:
385.412
SMILES:
OC(=O)c1cccc(COc2cccc(OCc3ccc4ccccc4n3)c2)c1
Structure:
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