Reaction Details  Report a problem with these data
Target
Carbonic anhydrase 4
Ligand
BDBM50279705
Substrate
n/a
Meas. Tech.
ChEMBL_1721601 (CHEMBL4136601)
Ki
298±n/a nM
Citation
 Angeli, A; Tanini, D; Capperucci, A; Supuran, CT Synthesis of Novel Selenides Bearing Benzenesulfonamide Moieties as Carbonic Anhydrase I, II, IV, VII, and IX Inhibitors. ACS Med Chem Lett 8:1213-1217 (2017) [PubMed]  Article
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV)
Type:
Enzyme
Mol. Mass.:
35037.98
Organism:
Homo sapiens (Human)
Description:
P22748
Residue:
312
Sequence:
MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLGPMLACLLAGFLR
  
Inhibitor
Name:
BDBM50279705
Synonyms:
CHEMBL4161289
Type:
Small organic molecule
Emp. Form.:
C12H12N2O4S2Se2
Mol. Mass.:
470.28
SMILES:
[#7]S(=O)(=O)c1ccc([Se;v2][Se;v2]c2ccc(cc2)S([#7])(=O)=O)cc1
Structure:
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