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Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50139772
Substrate
n/a
Meas. Tech.
ChEMBL_211324 (CHEMBL818983)
IC50
1800±n/a nM
Citation
 Poncet, J; Busquet, M; Roux, F; Pierré, A; Atassi, G; Jouin, P Synthesis and biological activity of chimeric structures derived from the cytotoxic natural compounds dolastatin 10 and dolastatin 15. J Med Chem 41:1524-30 (1998) [PubMed]  Article
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50139772
Synonyms:
22-oxovincaleukoblastine | leurocristine | vincristine
Type:
Small organic molecule
Emp. Form.:
C46H56N4O10
Mol. Mass.:
824.9576
SMILES:
CC[C@]1(O)C[C@H]2CN(C1)CCc1c([nH]c3ccccc13)[C@@](C2)(C(=O)OC)c1cc2c(cc1OC)N(C=O)[C@@H]1[C@]22CCN3CC=C[C@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC |r,c:49|
Structure:
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