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Target
Delta-type opioid receptor
Ligand
BDBM50496730
Substrate
n/a
Meas. Tech.
ChEMBL_1330172 (CHEMBL3224074)
Ki
>10000±n/a nM
Citation
 Prevatt-Smith, KM; Lovell, KM; Simpson, DS; Day, VW; Douglas, JT; Bosch, P; Dersch, CM; Rothman, RB; Kivell, B; Prisinzano, TE Potential Drug Abuse Therapeutics Derived from the Hallucinogenic Natural Product Salvinorin A. Medchemcomm 2:1217-1222 (2011) [PubMed]  Article
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50496730
Synonyms:
CHEMBL3219942
Type:
Small organic molecule
Emp. Form.:
C24H31NO8
Mol. Mass.:
461.5048
SMILES:
[H][C@@]12CC[C@@]3(C)[C@@H](C[C@H](OC(=O)NCC)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)c1ccoc1)C(=O)OC |r|
Structure:
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