Reaction Details  Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50049391
Substrate
n/a
Meas. Tech.
ChEMBL_32014 (CHEMBL649050)
Ki
3150±n/a nM
Citation
 Ji, XD; Melman, N; Jacobson, KA Interactions of flavonoids and other phytochemicals with adenosine receptors. J Med Chem 39:781-8 (1996) [PubMed]  Article
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50049391
Synonyms:
3,5,7-Trihydroxyflavone | 3,5,7-triOH-flavone | 3,5,7-trihydroxy-2-phenyl-4H-benzopyran-4-one | 3,5,7-trihydroxy-2-phenyl-4H-chromen-4-one | CHEMBL309490 | Galangin | Galangin (15) | Galangin (Gal) | cid_5281616 | norizalpinin
Type:
Small organic molecule
Emp. Form.:
C15H10O5
Mol. Mass.:
270.2369
SMILES:
Oc1cc(O)c2c(c1)oc(-c1ccccc1)c(O)c2=O
Structure:
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