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Target
Structural capsid protein
Ligand
BDBM50467395
Substrate
n/a
Meas. Tech.
ChEMBL_1557013 (CHEMBL3772497)
Kd
2800±n/a nM
Citation
 Machara, A; Lux, V; Ko?í?ek, M; Grantz ?a?ková, K; ?t?pánek, O; Kotora, M; Parkan, K; Pávová, M; Glass, B; Sehr, P; Lewis, J; Müller, B; Kräusslich, HG; Konvalinka, J Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds. J Med Chem 59:545-58 (2016) [PubMed]  Article
Target
Name:
Structural capsid protein
Synonyms:
Structural capsid protein | gag
Type:
PROTEIN
Mol. Mass.:
12762.23
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_106648
Residue:
115
Sequence:
ELERFAVNPALLETSEGCRQILGQLQPSLQTGSEELKSLFNTVATLYCVHQRIEVKDTKEALDKIEEEQNKSKKKAQQAQQAAAATGSSQVSQNYPIVQNLQGQMVHQPISPRTL
  
Inhibitor
Name:
BDBM50467395
Synonyms:
CHEMBL1229713
Type:
Small organic molecule
Emp. Form.:
C27H27N3O2
Mol. Mass.:
425.5222
SMILES:
CN(C(=O)[C@H](Cc1ccccc1)NC(=O)Cc1c(C)[nH]c2ccccc12)c1ccccc1 |r|
Structure:
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