Reaction Details  Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50051228
Substrate
n/a
Meas. Tech.
ChEMBL_29479 (CHEMBL640472)
Ki
471±n/a nM
Citation
 Baraldi, PG; Cacciari, B; Spalluto, G; Pineda de las Infantas y Villatoro, MJ; Zocchi, C; Dionisotti, S; Ongini, E Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives: potent and selective A(2A) adenosine antagonists. J Med Chem 39:1164-71 (1996) [PubMed]  Article
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50051228
Synonyms:
2-Furan-2-yl-7-(2-morpholin-4-yl-ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine | CHEMBL275636
Type:
Small organic molecule
Emp. Form.:
C16H18N8O2
Mol. Mass.:
354.3665
SMILES:
Nc1nc2n(CCN3CCOCC3)ncc2c2nc(nn12)-c1ccco1
Structure:
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