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Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM50059890
Substrate
n/a
Meas. Tech.
ChEMBL_2958 (CHEMBL617898)
Ki
62±n/a nM
Citation
 Monte, AP; Waldman, SR; Marona-Lewicka, D; Wainscott, DB; Nelson, DL; Sanders-Bush, E; Nichols, DE Dihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives. J Med Chem 40:2997-3008 (1997) [PubMed]  Article
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT-1C | 5-HT-2C | 5-HT1C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
51836.79
Organism:
Homo sapiens (Human)
Description:
P28335
Residue:
458
Sequence:
MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
  
Inhibitor
Name:
BDBM50059890
Synonyms:
2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b']difuran-4-yl)-ethylamine | CHEMBL316527
Type:
Small organic molecule
Emp. Form.:
C13H17NO3
Mol. Mass.:
235.279
SMILES:
COc1c2OCCc2c(CCN)c2CCOc12
Structure:
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