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Target
TYR_PHOSPHATASE_2 domain-containing protein
Ligand
BDBM50523085
Substrate
n/a
Meas. Tech.
ChEMBL_1888918 (CHEMBL4390595)
IC50
2200±n/a nM
Citation
 Cai, R; Jiang, H; Mo, Y; Guo, H; Li, C; Long, Y; Zang, Z; She, Z Ophiobolin-Type Sesterterpenoids from the Mangrove Endophytic Fungus  J Nat Prod 82:2268-2278 (2019) [PubMed]  Article
Target
Name:
TYR_PHOSPHATASE_2 domain-containing protein
Synonyms:
(PROTEIN-TYROSINE-PHOSPHATASE) (PTPase) | MPtpB | PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB | Phosphotyrosine protein phosphatase | Phosphotyrosine-protein phosphatase PTPB | Protein Tyrosine Phosphatase PTPB
Type:
Hydrolase
Mol. Mass.:
30152.45
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
276
Sequence:
MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
  
Inhibitor
Name:
BDBM50523085
Synonyms:
CHEMBL4583298
Type:
Small organic molecule
Emp. Form.:
C25H38O3
Mol. Mass.:
386.5674
SMILES:
[H][C@]12C[C@@]1(C)[C@]1([H])CCC(C(O)=O)=C1C[C@@]1(CO)CC[C@]3(C)CC[C@H](C(C)C)[C@@]3([H])[C@]21[H] |r,c:13|
Structure:
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