Reaction Details  Report a problem with these data
Target
Kallikrein-1
Ligand
BDBM50079380
Substrate
n/a
Meas. Tech.
ChEMBL_92369 (CHEMBL701583)
Ki
>10000000±n/a nM
Citation
 Sanders, TC; Seto, CT 4-Heterocyclohexanone-based inhibitors of the serine protease plasmin. J Med Chem 42:2969-76 (1999) [PubMed]  Article
Target
Name:
Kallikrein-1
Synonyms:
KLK1 | KLK1_HUMAN | Kallikrein 1 | Kallikrein-1 | Kidney/pancreas/salivary gland kallikrein | Tissue kallikrein
Type:
Enzyme
Mol. Mass.:
28874.69
Organism:
Homo sapiens (Human)
Description:
P06870
Residue:
262
Sequence:
MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAENS
  
Inhibitor
Name:
BDBM50079380
Synonyms:
3-[Bis-(6-amino-hexyl)-amino]-tetrahydro-thiopyran-4-one | CHEMBL318854
Type:
Small organic molecule
Emp. Form.:
C17H35N3OS
Mol. Mass.:
329.544
SMILES:
NCCCCCCN(CCCCCCN)C1CSCCC1=O
Structure:
Search PDB for entries with ligand similarity: