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Target
Group 10 secretory phospholipase A2
Ligand
BDBM50534276
Substrate
n/a
Meas. Tech.
ChEMBL_1928085 (CHEMBL4431157)
IC50
3800±n/a nM
Citation
 Giordanetto, F; Pettersen, D; Starke, I; Nordberg, P; Dahlström, M; Knerr, L; Selmi, N; Rosengren, B; Larsson, LO; Sandmark, J; Castaldo, M; Dekker, N; Karlsson, U; Hurt-Camejo, E Discovery of AZD2716: A Novel Secreted Phospholipase A ACS Med Chem Lett 7:884-889 (2016) [PubMed]  Article
Target
Name:
Group 10 secretory phospholipase A2
Synonyms:
Group X secretory phospholipase A2 | PA2GX_HUMAN | PLA2G10
Type:
PROTEIN
Mol. Mass.:
18153.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1442449
Residue:
165
Sequence:
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
  
Inhibitor
Name:
BDBM50534276
Synonyms:
CHEMBL4555962
Type:
Small organic molecule
Emp. Form.:
C24H23NO3
Mol. Mass.:
373.4443
SMILES:
C[C@@H](Cc1cccc(c1)-c1cc(Cc2ccccc2)ccc1C(N)=O)C(O)=O |r|
Structure:
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