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Target
Tubulin polymerization-promoting protein
Ligand
BDBM50099948
Substrate
n/a
Meas. Tech.
ChEMBL_925239 (CHEMBL3073731)
EC50
>100000±n/a nM
Citation
Young, DH; Tice, CM; Michelotti, EL; Roemmele, RC; Slawecki, RA; Rubio, FM; Rolling, JA Structure-activity relationships of phenylcyclohexene and biphenyl antitubulin compounds against plant and mammalian cells. Bioorg Med Chem Lett 11:1393-6 (2001) [PubMed]
More Info.:
Target
Name:
Tubulin polymerization-promoting protein
Synonyms:
25 kDa brain-specific protein | TPPP | TPPP_BOVIN
Type:
PROTEIN
Mol. Mass.:
23484.86
Organism:
Bos taurus
Description:
ChEMBL_106635
Residue:
218
Sequence:
MADSRPKPANKTPPKSPGEPAKDKAAKRLSLEAEGAGEGAAAAGAELSALEEAFRKFAVHGDARASGREMHGKNWSKLCRDCQVIDGRSVTVTDVDIVFSKIKGKSCRTITFEQFKEALEELAKKRFKDKSAEEAVREVHKLIEGKAPIISGVTKAISSPTVSRLTDTSKFTGSHKERFDPSGRGKGRAGRVDLVDESGYVPGYKHAGTYDQKVQGGK