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Target
Adenosine receptor A3
Ligand
BDBM50097423
Substrate
n/a
Meas. Tech.
ChEBML_29903
Ki
82±n/a nM
Citation
 van Tilburg, EW; van der Klein, PA; de Groote, M; Beukers, MW; IJzerman, AP Substituted 4-phenyl-2-(phenylcarboxamido)-1,3-thiazole derivatives as antagonists for the adenosine A(1) receptor. Bioorg Med Chem Lett 11:2017-9 (2001) [PubMed]
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50097423
Synonyms:
4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide | 4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide(LUF5417) | 4-methoxy-N-(3-phenyl-1,2,4-thiadiazol-5-yl)benzamide | CHEMBL305322 | LUF-5417
Type:
Small organic molecule
Emp. Form.:
C16H13N3O2S
Mol. Mass.:
311.358
SMILES:
COc1ccc(cc1)C(=O)Nc1nc(ns1)-c1ccccc1
Structure:
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