Reaction Details  Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50420167
Substrate
n/a
Meas. Tech.
ChEMBL_2050015 (CHEMBL4704714)
EC50
33884±n/a nM
Citation
 Xu, F; Zhao, Y; Zhou, H; Li, C; Zhang, X; Hou, T; Qu, L; Wei, L; Wang, J; Liu, Y; Liang, X Synthesis and evaluation of 3-(4-(phenoxymethyl)phenyl)propanoic acid and N-phenylbenzenesulfonamide derivatives as FFA4 agonists. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50420167
Synonyms:
CHEMBL2058533
Type:
Small organic molecule
Emp. Form.:
C23H21FO3
Mol. Mass.:
364.4094
SMILES:
Cc1ccc(cc1)-c1ccc(F)cc1COc1ccc(CCC(O)=O)cc1
Structure:
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