Target

Ligand

Substrate

Meas. Tech.

ChEMBL_2054935 (CHEMBL4709936)

Citation

 ?a?ewska, D; Bajda, M; Kaleta, M; Zar?ba, P; Doroz-P?onka, A; Siwek, A; Alachkar, A; Mogilski, S; Saad, A; Kuder, K; Olejarz-Maciej, A; Gody?, J; Stary, D; Sudo?, S; Wi?cek, M; Latacz, G; Walczak, M; Handzlik, J; Sadek, B; Malawska, B; Kie?-Kononowicz, K Rational design of new multitarget histamine H Eur J Med Chem 207:0 (2020) [PubMed]  Article

More Info.:

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Name:

Cholinesterase

Synonyms:

BCHE | Butyrylcholinesterase (BuChE) | CHLE_HORSE | Cholinesterase

Type:

Enzyme

Mol. Mass.:

65643.35

Organism:

Equus caballus (Horse)

Description:

P81908

Residue:

574

Sequence:

EEDIIITTKNGKVRGMNLPVLGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSNIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTELSEDCLYLNVWIPAPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLALSENPEAPGNMGLFDQQLALQWVQKNIAAFGGNPRSVTLFGESAGAASVSLHLLSPRSQPLFTRAILQSGSSNAPWAVTSLYEARNRTLTLAKRMGCSRDNETEMIKCLRDKDPQEILLNEVFVVPYDTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKRTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPRVSEFGRESILFHYMDWLDDQRAENYREALDDVVGDYNIICPALEFTRKFSELGNDAFFYYFEHRSTKLPWPEWMGVMHGYEIEFVFGLPLERRVNYTRAEEILSRSIMKRWANFAKYGNPNGTQNNSTRWPVFKSTEQKYLTLNTESPKVYTKLRAQQCRFWTLFFPKVLELTGNIDEAEREWKAGFHRWNNYMMDWKNQFNDYTSKKESCSDF

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Blast E-value cutoff:

Name:

BDBM50556132

Synonyms:

CHEMBL4783624

Type:

Small organic molecule

Emp. Form.:

C24H28ClNO3

Mol. Mass.:

413.937

SMILES:

Clc1ccc2oc3ccc(OCCCCCN4CCCCCC4)cc3c(=O)c2c1

Structure:

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