Reaction Details  Report a problem with these data
Target
Prostaglandin E2 receptor EP2 subtype
Ligand
BDBM50117689
Substrate
n/a
Meas. Tech.
ChEBML_158301
Ki
10000±n/a nM
Citation
 Gallant, M; Belley, M; Carrière, MC; Chateauneuf, A; Denis, D; Lachance, N; Lamontagne, S; Metters, KM; Sawyer, N; Slipetz, D; Truchon, JF; Labelle, M Structure-activity relationship of triaryl propionic acid analogues on the human EP3 prostanoid receptor. Bioorg Med Chem Lett 13:3813-6 (2003) [PubMed]
Target
Name:
Prostaglandin E2 receptor EP2 subtype
Synonyms:
PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor
Type:
Enzyme
Mol. Mass.:
39775.71
Organism:
Homo sapiens (Human)
Description:
P43116
Residue:
358
Sequence:
MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
  
Inhibitor
Name:
BDBM50117689
Synonyms:
CHEMBL87371 | Thiophene-2-sulfonic acid [(E)-3-(3',4'-dichloro-biphenyl-2-yl)-acryloyl]-amide
Type:
Small organic molecule
Emp. Form.:
C19H13Cl2NO3S2
Mol. Mass.:
438.347
SMILES:
Clc1ccc(cc1Cl)-c1ccccc1\C=C\C(=O)NS(=O)(=O)c1cccs1
Structure:
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