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Target
5-hydroxytryptamine receptor 6
Ligand
BDBM50582604
Substrate
n/a
Meas. Tech.
ChEMBL_2155124 (CHEMBL5039784)
Ki
>10000±n/a nM
Citation
 Lee, J; Kwag, R; Lee, S; Kim, D; Woo, J; Cho, Y; Kim, HJ; Kim, J; Jeon, B; Choo, H Discovery of G Protein-Biased Ligands against 5-HT J Med Chem 64:7453-7467 (2021) [PubMed]  Article
Target
Name:
5-hydroxytryptamine receptor 6
Synonyms:
5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
46968.43
Organism:
Homo sapiens (Human)
Description:
P50406
Residue:
440
Sequence:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN
  
Inhibitor
Name:
BDBM50582604
Synonyms:
CHEMBL5094234
Type:
Small organic molecule
Emp. Form.:
C17H21Cl2NO
Mol. Mass.:
326.261
SMILES:
Cl.CCNCCc1ccc(Cl)c(c1)-c1ccccc1OC
Structure:
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