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Target
Vitamin K epoxide reductase complex subunit 1
Ligand
BDBM50166637
Substrate
n/a
Meas. Tech.
ChEMBL_305987 (CHEMBL832974)
IC50
40±n/a nM
Citation
 Chen, DU; Kuo, PY; Yang, DY Design and synthesis of novel diphenacoum-derived, conformation-restricted vitamin K 2,3-epoxide reductase inhibitors. Bioorg Med Chem Lett 15:2665-8 (2005) [PubMed]  Article
Target
Name:
Vitamin K epoxide reductase complex subunit 1
Synonyms:
VKOR1_BOVIN | VKORC1 | Vitamin k epoxide reductase complex subunit 1 isoform 1
Type:
PROTEIN
Mol. Mass.:
17977.60
Organism:
Bos taurus
Description:
ChEMBL_305987
Residue:
163
Sequence:
MGATWRSPGWVRLALCLAGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWGRGFGLVEHVLGKDSILNQSNSIFGCIFYTLQLLLGCLQGRWASVLLRLSCLVSLAGSVYLAWILFFVLYDFCIVCITTYAINVGLTVLSFREVQGPQGKVKGH
  
Inhibitor
Name:
BDBM50166637
Synonyms:
2'-Biphenyl-4-yl-4-hydroxy-3',4'-dihydro-2'H-[3,4']bichromenyl-2-one | CHEMBL191979
Type:
Small organic molecule
Emp. Form.:
C30H22O4
Mol. Mass.:
446.4933
SMILES:
Oc1c(C2CC(Oc3ccccc23)c2ccc(cc2)-c2ccccc2)c(=O)oc2ccccc12
Structure:
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