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Target
5-hydroxytryptamine receptor 5A
Ligand
BDBM50029799
Substrate
n/a
Meas. Tech.
ChEMBL_2275536
Ki
>10000±n/a nM
Citation
 Beato, A; Gori, A; Boucherle, B; Peuchmaur, M; Haudecoeur, R ?-Carboline as a Privileged Scaffold for Multitarget Strategies in Alzheimer's Disease Therapy. J Med Chem 64:1392-1422 (2021) [PubMed]
Target
Name:
5-hydroxytryptamine receptor 5A
Synonyms:
5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A
Type:
Enzyme
Mol. Mass.:
40266.25
Organism:
Homo sapiens (Human)
Description:
P47898
Residue:
357
Sequence:
MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
  
Inhibitor
Name:
BDBM50029799
Synonyms:
7-Methoxy-1-methyl-2,9-dihydro-1H-beta-carboline | 7-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline | 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole | CHEMBL2089157 | CHEMBL340807 | HARMALINE
Type:
Small organic molecule
Emp. Form.:
C13H14N2O
Mol. Mass.:
214.2631
SMILES:
COc1ccc2c3CCN=C(C)c3[nH]c2c1 |t:9|
Structure:
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