Reaction Details  Report a problem with these data
Target
CDGSH iron-sulfur domain-containing protein 1
Ligand
BDBM50614904
Substrate
n/a
Meas. Tech.
ChEMBL_2299223
EC50
106700±n/a nM
Citation
 Newton, E; Starcovic, SA; Menze, M; Konkle, ME; Long, TE; Hazlehurst, LA; Huber, JD; Robart, AR; Geldenhuys, WJ Development of a fluorescence screening assay for binding partners of the iron-sulfur mitochondrial protein mitoNEET. Bioorg Med Chem Lett 89:0 (2023) [PubMed]
Target
Name:
CDGSH iron-sulfur domain-containing protein 1
Synonyms:
C10orf70 | CISD1 | CISD1_HUMAN | MitoNEET | ZCD1
Type:
PROTEIN
Mol. Mass.:
12206.48
Organism:
Homo sapiens (Human)
Description:
ChEMBL_766432
Residue:
108
Sequence:
MSLTSSSSVRVEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKAMINLHIQKDNPKIVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKKKET
  
Inhibitor
Name:
BDBM50614904
Synonyms:
CHEMBL5275408
Type:
Small organic molecule
Emp. Form.:
C20H17ClN2O4S
Mol. Mass.:
416.878
SMILES:
NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccc(cc2)-c2ccccc2)cc1Cl
Structure:
Search PDB for entries with ligand similarity: