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Target
Solute carrier organic anion transporter family member 2B1
Ligand
BDBM50249470
Substrate
n/a
Meas. Tech.
ChEMBL_2299843
IC50
101000±n/a nM
Citation
 Peng, T; Liu, S; Li, Y; Zhang, H; Hagenbuch, B; Gui, C Investigating the interactions of flavonoids with human OATP2B1: inhibition assay, IC RSC Med Chem 14:890-898 (2023) [PubMed]
Target
Name:
Solute carrier organic anion transporter family member 2B1
Synonyms:
KIAA0880 | OATP-B | OATP-RP2 | OATP2B1
Type:
PROTEIN
Mol. Mass.:
76717.01
Organism:
Homo sapiens
Description:
ChEMBL_104065
Residue:
709
Sequence:
MGPRIGPAGEVPQVPDKETKATMGTENTPGGKASPDPQDVRPSVFHNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPKEMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGITHQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVVEGNPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTKESRSSPAVEQQLLVSGPGKKPEDSRV
  
Inhibitor
Name:
BDBM50249470
Synonyms:
CHEBI:28327 | Prunin
Type:
Small organic molecule
Emp. Form.:
C21H22O10
Mol. Mass.:
434.3934
SMILES:
OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C[C@H](Oc3c2)c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r|
Structure:
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