Reaction Details
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Target
Hematopoietic prostaglandin D synthase
Ligand
BDBM50615790
Substrate
n/a
Meas. Tech.
ChEMBL_2304418
EC50
280±n/a nM
Citation
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More Info.:
Target
Name:
Hematopoietic prostaglandin D synthase
Synonyms:
2.5.1.18 | 5.3.99.2 | GST class-sigma | Glutathione S-transferase | Glutathione-dependent PGD synthase | Glutathione-requiring prostaglandin D synthase | Gsts | H-PGDS | HPGDS_RAT | Hematopoietic prostaglandin D synthase | Hpgds | Pgds | Prostaglandin-H2 D-isomerase | Ptgds2
Type:
PROTEIN
Mol. Mass.:
23295.19
Organism:
Rattus norvegicus
Description:
ChEMBL_118881
Residue:
199
Sequence:
MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWAEENQDLKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIYPRLVSLRNKVQAIPAISAWILKRPQTKL
Inhibitor
Name:
BDBM50615790
Synonyms:
CHEMBL5283878
Type:
Small organic molecule
Emp. Form.:
C19H23N3O2
Mol. Mass.:
325.4048
SMILES:
CC(C)(O)[C@H]1C[C@@H](C1)NC(=O)c1cnc2nc(ccc2c1)C1CC1 |r,wU:6.8,wD:4.3,(7.81,3.82,;7.04,2.48,;6.27,3.82,;8.38,1.71,;5.71,1.71,;4.22,2.11,;3.82,.6,;5.3,.2,;2.48,-.17,;1.15,.6,;1.15,2.14,;-.18,-.17,;-.18,-1.71,;-1.52,-2.48,;-2.85,-1.71,;-4.17,-2.48,;-5.5,-1.71,;-5.5,-.19,;-4.19,.59,;-2.85,-.18,;-1.52,.6,;-6.83,-2.48,;-8.38,-2.48,;-7.61,-3.82,)|