Reaction Details
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Target
Hematopoietic prostaglandin D synthase
Ligand
BDBM50615804
Substrate
n/a
Meas. Tech.
ChEMBL_2304418
EC50
1000±n/a nM
Citation
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More Info.:
Target
Name:
Hematopoietic prostaglandin D synthase
Synonyms:
2.5.1.18 | 5.3.99.2 | GST class-sigma | Glutathione S-transferase | Glutathione-dependent PGD synthase | Glutathione-requiring prostaglandin D synthase | Gsts | H-PGDS | HPGDS_RAT | Hematopoietic prostaglandin D synthase | Hpgds | Pgds | Prostaglandin-H2 D-isomerase | Ptgds2
Type:
PROTEIN
Mol. Mass.:
23295.19
Organism:
Rattus norvegicus
Description:
ChEMBL_118881
Residue:
199
Sequence:
MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWAEENQDLKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIYPRLVSLRNKVQAIPAISAWILKRPQTKL
Inhibitor
Name:
BDBM50615804
Synonyms:
CHEMBL5283710
Type:
Small organic molecule
Emp. Form.:
C21H27FN4O2
Mol. Mass.:
386.4631
SMILES:
CC(C)(O)[C@H]1CC[C@@H](CC1)NC(=O)c1cnc2nc(ccc2c1)N1CC(F)C1 |r,wU:7.10,wD:4.3,(9.04,4.3,;8.27,2.97,;7.5,4.3,;9.61,2.2,;6.94,2.2,;5.6,2.97,;4.27,2.2,;4.27,.66,;5.6,-.11,;6.94,.66,;2.94,-.11,;1.6,.66,;1.6,2.2,;.27,-.11,;.27,-1.65,;-1.06,-2.42,;-2.4,-1.65,;-3.72,-2.41,;-5.05,-1.65,;-5.05,-.13,;-3.73,.65,;-2.4,-.12,;-1.07,.66,;-6.38,-2.42,;-6.78,-3.93,;-8.27,-3.53,;-9.61,-4.3,;-7.87,-2.02,)|