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Target
Adenosine receptor A3
Ligand
BDBM50252756
Substrate
n/a
Meas. Tech.
ChEMBL_539465 (CHEMBL1028961)
Ki
6.3±n/a nM
Citation
 Jeong, LS; Pal, S; Choe, SA; Choi, WJ; Jacobson, KA; Gao, ZG; Klutz, AM; Hou, X; Kim, HO; Lee, HW; Lee, SK; Tosh, DK; Moon, HR Structure-activity relationships of truncated D- and l-4'-thioadenosine derivatives as species-independent A3 adenosine receptor antagonists. J Med Chem 51:6609-13 (2008) [PubMed]  Article
Target
Name:
Adenosine receptor A3
Synonyms:
AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3
Type:
PROTEIN
Mol. Mass.:
36643.73
Organism:
Rattus norvegicus
Description:
ChEMBL_479910
Residue:
320
Sequence:
MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
  
Inhibitor
Name:
BDBM50252756
Synonyms:
(2R,3R,4S)-2-(6-(3-Bromobenzylamino)-9H-purin-9-yl)-tetrahydrothiophene-3,4-diol | CHEMBL522856
Type:
Small organic molecule
Emp. Form.:
C16H16BrN5O2S
Mol. Mass.:
422.3
SMILES:
O[C@@H]1CS[C@H]([C@@H]1O)n1cnc2c(NCc3cccc(Br)c3)ncnc12 |r|
Structure:
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