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Target
Carboxypeptidase B
Ligand
BDBM50296415
Substrate
n/a
Meas. Tech.
ChEMBL_580786 (CHEMBL1059768)
Ki
1400±n/a nM
Citation
 Fernández, D; Avilés, FX; Vendrell, J A new type of five-membered heterocyclic inhibitors of basic metallocarboxypeptidases. Eur J Med Chem 44:3266-71 (2009) [PubMed]  Article
Target
Name:
Carboxypeptidase B
Synonyms:
CPB
Type:
Enzyme
Mol. Mass.:
48382.46
Organism:
Helicoverpa zea (Corn earworm moth) (Heliothis zea)
Description:
Q3T905
Residue:
429
Sequence:
MKFLLVLALCAVVYAKHEAYIGWKSYYVGVATDAQAKALEPLIQKYELDFLSHPTKSREGVVLVKPQHQAGFVQDIEAGGITYRIHADDVKRQLEFDDQLIEMQRMSSFTRTAGRQLPYDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFIDGGIHAREWISPPSVTWAIHKLVEDVTENDLLEKFDWILLPVVNPDGYKYTFTNERFWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDILHEHLARMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPYTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWEGIVVGARRAGDLFRK
  
Inhibitor
Name:
BDBM50296415
Synonyms:
4-(5-(2-chlorobenzylthio)-1,3,4-oxadiazol-2-yl)-N-(thiophen-2-ylmethyl)benzenesulfonamide | CHEMBL563825
Type:
Small organic molecule
Emp. Form.:
C20H16ClN3O3S3
Mol. Mass.:
478.007
SMILES:
Clc1ccccc1CSc1nnc(o1)-c1ccc(cc1)S(=O)(=O)NCc1cccs1
Structure:
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