Reaction Details  Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50297170
Substrate
n/a
Meas. Tech.
ChEMBL_581432 (CHEMBL1055676)
Ki
10.6±n/a nM
Citation
 Fujii, H; Ogawa, R; Ohata, K; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Nagase, H Aerobic oxidation of indolomorphinan without the 4,5-epoxy bridge and subsequent rearrangement of the oxidation product to spiroindolinonyl-C-normorphinan derivative. Bioorg Med Chem 17:5983-8 (2009) [PubMed]  Article
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50297170
Synonyms:
7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Oxymorphone | 7-spiroindanyloxymorphone | CHEMBL399708 | SIOM | Spiroindanyloxymorphone
Type:
Small organic molecule
Emp. Form.:
C25H25NO4
Mol. Mass.:
403.4703
SMILES:
CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC1(Cc2ccccc2C1)C4=O)ccc5O
Structure:
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