Reaction Details  Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50301306
Substrate
n/a
Meas. Tech.
ChEMBL_599309 (CHEMBL1041037)
EC50
42±n/a nM
Citation
 Worm, K; Weaver, DG; Green, RC; Saeui, CT; Dulay, DM; Barker, WM; Cassel, JA; Stabley, GJ; DeHaven, RN; LaBuda, CJ; Koblish, M; Brogdon, BL; Smith, SA; Dolle, RE Discovery of N-(3-(morpholinomethyl)-phenyl)-amides as potent and selective CB2 agonists. Bioorg Med Chem Lett 19:5004-8 (2009) [PubMed]  Article
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Human
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50301306
Synonyms:
2-methyl-N-(4-methyl-3-(morpholinomethyl)-5-(trifluoromethyl)phenyl)cyclohexanecarboxamide | CHEMBL579194
Type:
Small organic molecule
Emp. Form.:
C21H29F3N2O2
Mol. Mass.:
398.4624
SMILES:
CC1CCCCC1C(=O)Nc1cc(CN2CCOCC2)c(C)c(c1)C(F)(F)F
Structure:
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